Definitely the ideal combination
Based on the latest findings of breast milk research, the Nutritional Science department of HiPP has developed a new generation of infant milk: HiPP COMBIOTIC®.
Natural probiotic
- Lactobacillus fermentum hereditum® CECT5716
- unchanged original lactic acid culture from breast milk1, 2, 3
- a primary coloniser of the intestine4
- supports a healthy intestinal flora5
- contributes to modulation of immune response6, 7
Proven prebiotic: GOS
- galacto-oligosaccharides obtained from organic lactose
- stool consistency and frequency similar to breastfed children8–11, 5
- promotes the growth of beneficial intestinal bacteria8-10, 5
- proven to be safe12
Clinical studies prove: Safety & significantly fewer infections
HiPP ORGANIC COMBIOTIC® supports the development of a healthy intestinal microbiota with its synbiotic composition1,2:
Clinical studies1, 2 prove:
- combination of pro- and prebiotics is safe and beneficial
- significantly fewer infections
- combination of GOS + L. fermentum significantly better than prebiotic (GOS) alone
References
1 Maldonado J et al. J Pediatr Gastroenterol Nutr 2012; 54(1):55–61
2 Gil-Campos M et al. Pharmacol Res 2012; 65(2):231–238
3 Maldonado-Lobon JA et al. Pharmacol Res 2015; 95–96:12–19
1 Maldonado J et al. J Pediatr Gastroenterol Nutr 2012; 54(1):55–61
2 Gil-Campos M et al. Pharmacol Res 2012; 65(2):231–238
3 Maldonado-Lobon JA et al. Pharmacol Res 2015; 95–96:12–19
Important palmitic acid
- saturated fatty acids predominate in breast milk
- important for good tolerability of formula13
> less watery and more yellowy stools (similar to those of breastfed children)
Omega 3 and 6 LCP
- evidence-based and recommended14
- important for cognitive and visual development
- optimum ratio of omega 3 and 6 LCP (DHA and ARA)
Appropriately low protein content
- < 2.0 g/100 kcal, tailored to physiological needs15
- obtained from high-quality organic milk and whey
HiPP ORGANIC COMBIOTIC® supplies all the key, high-quality macro- and micronutrients in the appropriate quantities.
Suitable HiPP info material
HiPP COMBIOTIC® Folder (AL48733)
Professional Information: Tried-and-tested formula. Evidence-based development.
HiPP Scientific Dossier L.ferm. GOS (AL47836)
L. fermentum CECT5716 and Galacto-oligosaccharides in HiPP ORGANIC COMBIOTIC® formulae.
References:
1 Martin R et al. J Pediatr 2003; 143(6): 754–758
2 Martin R et al. J Hum Lact 2005; 21(1): 8–17
3 Lara-Villoslada F et al. Br J Nutr 2007; 98(suppl 1): 96–100
4 Blaut M & Loh C in: Bischoff¬ SC: Probiotika, Präbiotika und Synbiotika; Thieme 2009; 2-23
5 Ben XM et al. World J Gastroenterol 2008; 14(42): 6564–6568
6 Olivares M et al. Nutr 2007; 23(3): 254–260
7 Perez-Cano FJ et al. Immunobiology 2010; 215(12): 996–1004
8 Ben XM et al. Chinese Medical Journal 2004; 117(6): 927–931
9 Fanaro S et al. J Pediatr Gastroenterol Nutr. 2009; 48: 82–88
10 Sierra C et al. Eur J Nutr 2015; 54(1):89–99
11 Ashley C et al. 2012 Nutrition Journal 2012; 11: 38
12 FDA. 2008; GRAS Notices GRN No. 236
13 Lloyd B et al. Pediatrics 1999; 103(1):e7
14 Koletzko B et al. J Perinat Med 2008; 36(1): 5–14
15 Koletzko B et al. Am J Clin Nutr 2009; 89(6): 1836–1845
HiPP for Health Care Professionals