HiPP for Health Care Professionals

New data in AJCN: HiPP COMBIOTIC^® shows positive effects on gut microbiota profiles

06.2023

The two studies GOLF I & GOLF II (GO= GOS, LF= L. fermentum) investigated the safety and effects of infant formula with pre- and probiotics.

New data from the GOLF III trial in the American Journal of Clinical Nutrition (AJCN) show: Synbiotic infant formula fortified with GOS and Limosilactobacillus fermentum CECT 5716 leads to similar intestinal parameters as in breastfed infants.¹

* as relates to 4-month-old children with a high bifidobacteria population gut microbiota and intestinal environment more similar to breastded infants.

The new GOLF III trial shows:

The abundance of bifidobacteria in infants of the intervention group does not differ significantly from breastfed infants.

The stool pH in infants of the intervention group is significantly lower than in infants of the control group. It is similar to the stool pH in breastfed infants.

The water content in the stool is significantly higher in infants of the intervention group and comparable to breastfed infants.

Conclusion

A synbiotic infant formula with L. fermentum CECT5716 and GOS supports a gut microbiota and intestinal environment more similar to breastfed infants.

Original study (open access)

Reference:
(1) Lagkouvardos I et al. Early life gut microbiota profi les linked to synbiotic formula eff ects: a radomized clinical trial in European infants. Am J Clin Nutr 2023; 117 (2): 326–339.