Author Prof. J. Spranger, University Department of Pediatrics Mainz
Previous studies have highlighted the risk of premature brain ageing in obese adults, seen in MRI scans through cortical atrophy . A recent comparative study of more than 1,000 adults has revealed that the frontal lobe and left temporal lobe are particularly affected. This pattern corresponds with that of Alzheimer's disease . Further investigation of ß-amyloid, however, ruled this disease out, suggesting this must be an obesity-specific kind of brain atrophy.