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06.2023
The two studies GOLF I & GOLF II (GO= GOS, LF= L. fermentum) investigated the safety and effects of infant formula with pre- and probiotics.
New data from the GOLF III trial in the American Journal of Clinical Nutrition (AJCN) show: Synbiotic infant formula fortified with GOS and Limosilactobacillus fermentum CECT 5716 leads to similar intestinal parameters as in breastfed infants.1
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The new GOLF III trial shows:
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The abundance of bifidobacteria in infants of the intervention group does not differ significantly from breastfed infants.
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The stool pH in infants of the intervention group is significantly lower than in infants of the control group. It is similar to the stool pH in breastfed infants.
![](/fileadmin/media/HCP.hipp.com/images/Content/GOLF_III_Grafik4_PDF_41934.png)
The water content in the stool is significantly higher in infants of the intervention group and comparable to breastfed infants.
Conclusion
A synbiotic infant formula with L. fermentum CECT5716 and GOS supports a gut microbiota and intestinal environment more similar to breastfed infants.
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Reference:
(1) Lagkouvardos I et al. Early life gut microbiota profi les linked to synbiotic formula eff ects: a radomized clinical trial in European infants. Am J Clin Nutr 2023; 117 (2): 326–339.
Suitable HiPP info material
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HiPP COMBIOTIC® shows positive effects on gut microbiota profiles.